POTENSI TERIPANG Stichopus japonicus SEBAGAI ANTIJAMUR, ANTIOKSIDAN, DAN PENGHAMBATAN TIROSINASE

Penulis

  • Amir Husni Penulis

Kata Kunci:

POTENSI TERIPANG Stichopus japonicus SEBAGAI ANTIJAMUR, ANTIOKSIDAN, DAN PENGHAMBATAN TIROSINASE

Abstrak

Buku ini mengupas tuntas potensi biologis dan manfaat teripang laut Stichopus japonicus dalam berbagai bidang, seperti farmasi, kosmetik, dan kesehatan. Bab 1 menjelaskan pengantar mengenai aplikasi ekstrak teripang yang meliputi perannya dalam inovasi produk berbasis bioaktif. Bab 2 menyajikan informasi lengkap tentang biologi dan ekologi Stichopus japonicus, dari habitat hingga siklus hidupnya. Bab 3 membahas biofungsional teripang, menyoroti kandungan senyawa aktif yang memiliki nilai kesehatan. Bab 4 menguraikan teknik ekstraksi dan karakterisasi senyawa bioaktif untuk menjamin kualitas dan efektivitasnya. Bab 5 hingga 7 menampilkan fokus utama buku ini, yaitu potensi teripang sebagai antijamur, antioksidan, dan agen penghambat tirosinase, yang menjadikannya prospek dalam pengembangan terapi antijamur, produk anti-penuaan, dan pencerah kulit. Buku ini menjadi referensi penting bagi peneliti, akademisi, dan praktisi di bidang bioteknologi laut dan kesehatan.

Referensi

Aggarwal, B. B., & Harikumar, K. B. (2009). "Potential therapeutic effects of curcumin, the anti-inflammatory agent from turmeric (Curcuma longa)." International Journal of Biochemistry & Cell Biology, 41(1), 40–59.

Althunibat, O. Y., Hashim, R. B., Taher, M., Daud, J. M., Ikeda, M. A., & Zali, I. (2009). "In vitro antioxidant and antiproliferative activities of three Malaysian sea cucumber species." European Journal of Scientific Research, 37(3), 376–387.

Atkins, P., & de Paula, J. (2010). Physical Chemistry (9th ed.). Oxford University Press.

Bordbar, S., Anwar, F., & Saari, N. (2011). "High-value components and bioactives from sea cucumbers for functional foods—a review." Marine Drugs, 9(10), 1761–1805.

Briganti, S., Camera, E., & Picardo, M. (2003). "Chemical and instrumental approaches to treat hyperpigmentation." Pigment Cell Research, 16(2), 101–110.

Brunner, G. (1994). Gas Extraction: An Introduction to Fundamentals of Supercritical Fluids and the Application to Separation Processes. Springer.

Calder, P. C. (2006). "n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases." The American Journal of Clinical Nutrition, 83(6), S1505–S1519.

Calder, P. C. (2013). "Omega-3 polyunsaturated fatty acids and inflammatory processes: Nutrition or pharmacology?" British Journal of Clinical Pharmacology, 75(3), 645–662.

Camargo F. B. Jr., L. R. Gaspar and P. M. Maia Campos. 2011. “Skin Moisturizing Effects of Panthenol-Based Formulations,” Journal of Cosmetic Science, Vol. 62, No. 4, pp. 361-370.

Chang, T. S. (2009). "An updated review of tyrosinase inhibitors." International Journal of Molecular Sciences, 10(6), 2440–2475.

Chemat, F., & Vian, M. A. (2014). Alternative Solvents for Natural Products Extraction. Springer.

Chen, J. (2003) Overview of Sea Cucumber Farming and Sea Ranching Practices in China. SPC Beche-de-mer Information Bulletin, 18, 18-23.

Claridge, T. D. W. (2008). High-Resolution NMR Techniques in Organic Chemistry (2nd ed.). Elsevier Science.

Conand, C. (2006). Sea cucumber biology, taxonomy, distribution and conservation status. In Advances in sea cucumber aquaculture and management (pp. 33-50).

Costantini, L., Molinari, R., Farinon, B., & Merendino, N. (2017). "Impact of omega-3 fatty acids on the gut microbiota." International Journal of Molecular Sciences, 18(12), 2645. doi:10.3390/ijms18122645

Cullity, B. D., & Stock, S. R. (2001). Elements of X-Ray Diffraction (3rd ed.). Prentice Hall.

D’Orazio, J., Jarrett, S., Amaro-Ortiz, A., & Scott, T. (2013). "UV radiation and the skin." International Journal of Molecular Sciences, 14(6), 12222–12248.

Davies, J., & Davies, D. (2010). Origins and evolution of antibiotic resistance. Microbiology and Molecular Biology Reviews, 74(3), 417-433.

Dewick, P. M. (2002). Medicinal Natural Products: A Biosynthetic Approach (2nd ed.). John Wiley & Sons.

Dewick, P. M. (2009). Medicinal Natural Products: A Biosynthetic Approach (3rd ed.). Wiley.

Fleming, A. (1929). On the antibacterial action of cultures of a Penicillium, with special reference to their use in the isolation of B. influenzae. British Journal of Experimental Pathology, 10(3), 226.

Friedman, K., Purcell, S., Bell, J., & Hair, C. (2008). Sea cucumber fisheries: a manager’s toolbox. ACIAR Monograph No. 135.

Hamel, J. F., & Mercier, A. (2008). Population status, fisheries, and trade of sea cucumbers in temperate areas of the Northern Hemisphere. In Sea Cucumbers: A Global Review of Fisheries and Trade (pp. 257-292). FAO Fisheries and Aquaculture Technical Paper No. 516.

Harborne, J. B. (1998). Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis (3rd ed.). Springer Science & Business Media.

Harris, D.C. and Lucy, C.A. (2016) Quantitative Chemical Analysis. 9th Edition, W.H. Freeman & Company, New York, NY.

Hoffmann, E. D., & Stroobant, V. (2007). Mass Spectrometry: Principles and Applications (3rd ed.). John Wiley & Sons.

Houghton, P. J., & Raman, A. (1998). Laboratory Handbook for the Fractionation of Natural Extracts. Springer.

Janakiram, N. B., Mohammed, A., & Rao, C. V. (2015). "Sea cucumber metabolites as potent anticancer agents." Marine Drugs, 13(5), 2909–2923. doi:10.3390/md13052909

Janakiram, N. B., Mohammed, A., & Rao, C. V. (2015). Sea Cucumbers Metabolites as Potent Anti-Cancer Agents. Marine Drugs, 13(5), 2909-2923.

Jenkins, R., & Snyder, R. L. (1996). Introduction to X-Ray Powder Diffractometry. Wiley.

Kang, J. X., & Weylandt, K. H. (2008). "Modulation of inflammatory cytokines by omega-3 fatty acids." Sub-cellular Biochemistry, 49, 133–143.

Kang, K. H., Kwon, J. Y., & Kim, J. M. (2003). A beneficial co-culture system for sea cucumber (Stichopus japonicus) and seaweed (Undaria pinnatifida). Aquaculture, 216(1-4), 87-93.

Kaufmann, B., & Christen, P. (2002). Recent extraction techniques for natural products: microwave‐assisted extraction and pressurised solvent extraction. Phytochemical Analysis: An International Journal of Plant Chemical and Biochemical Techniques, 13(2), 105-113.

Kerr, A. M. (1994). The Shallow-water Holothuroids (Echinodermata) of the Commonwealth of the Northern Mariana Islands. Micronesica, 38(1), 123–135.

Khan, N., & Mukhtar, H. (2013). "Tea polyphenols for health promotion." Life Sciences, 81(7), 519–533.

Lambert, J. D., & Elias, R. J. (2010). "The antioxidant and pro-oxidant activities of green tea polyphenols: A role in cancer prevention and treatment." Food and Function, 1(5), 452–465.

Levy, S. B., & Marshall, B. (2004). Antibacterial resistance worldwide: Causes, challenges and responses. Nature Medicine, 10(12), S122-S129.

Macomber, R. S. (1998). A Complete Introduction to Modern NMR Spectroscopy. John Wiley & Sons.

MacTavish, T., Stenton-Dozey, J., Vopel, K., & Savage, C. (2012). Deposit-feeding sea cucumbers enhance mineralization and nutrient cycling in organically enriched coastal sediments. PLOS ONE, 7(11), e50031.

Maeda, K., & Fukuda, M. (1996). "In vitro effectiveness of several whitening cosmetic components in human melanocytes." Journal of the Society of Cosmetic Chemists, 47(1), 27–39.

Mendes, R. L., Nobre, B. P., Cardoso, M. T., Pereira, A. P., & Palavra, A. F. (2003). Supercritical carbon dioxide extraction of compounds with pharmaceutical importance from microalgae. Inorganica Chimica Acta, 356, 328-334.

Mendis, E., & Kim, S. K. (2011). "Present and future prospects of seaweeds in developing functional foods." Advances in Food and Nutrition Research, 64, 1–15.

Mitra, S. (2003). Sample Preparation Techniques in Analytical Chemistry. Wiley-Interscience.

Mukherjee, P. K. (2019). Quality Control and Evaluation of Herbal Drugs: Evaluating Natural Products and Traditional Medicine. Elsevier.

Pangestuti, R., & Arifin, Z. (2018). "Functional properties of sea cucumbers and their bioactive compounds for potential therapeutic applications: A review." Journal of Functional Foods, 41, 24–36.

Pangestuti, R., & Arifin, Z. (2018). Medicinal and health benefit effects of functional sea cucumbers. Journal of Traditional and Complementary Medicine, 8(3), 341-351.

Pillaiyar, T., Manickam, M., & Namasivayam, V. (2017). "Skin whitening agents: Medicinal chemistry perspective of tyrosinase inhibitors." Journal of Enzyme Inhibition and Medicinal Chemistry, 32(1), 403–425.

Podolsky, S. H. (2018). The evolving response to antibiotic resistance (1945–2018). Palgrave Communications, 4(1), 1-8.

Prasad, A. S. (2008). "Zinc in human health: Effect of zinc on immune cells." Molecular Medicine, 14(5–6), 353–357.

Purcell, S. W., Conand, C., Uthicke, S., & Byrne, M. (2016). Ecological roles of exploited sea cucumbers. Oceanography and Marine Biology: An Annual Review, 54, 367-386.

Purcell, S. W., Samyn, Y., & Conand, C. (2012). Commercially important sea cucumbers of the world. FAO Species Catalogue for Fishery Purposes No. 6. FAO.

Rajanbabu, V., & Chen, J. Y. (2011). " Applications of antimicrobial peptides from fish and perspectives for the future." Marine Drugs,

Rayman, M. P. (2000). "The importance of selenium to human health." The Lancet, 356(9225), 233–241.

Rice-Evans, C. A., Miller, N. J., & Paganga, G. (1997). "Antioxidant properties of phenolic compounds." Trends in Plant Science, 2(4), 152–159.

Rios, J. L., & Recio, M. C. (2005). Medicinal plants and antimicrobial activity. Journal of Ethnopharmacology, 100(1-2), 80-84.

Saewan, N., & Jimtaisong, A. (2015). "Natural products as photoprotection." Journal of Cosmetic Dermatology, 12(1), 19–31.

Sarker, S. D., Latif, Z., & Gray, A. I. (2006). Natural Products Isolation (2nd ed.). Humana Press.

Serhan, C. N., Chiang, N., & Van Dyke, T. E. (2008). "Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators." Nature Reviews Immunology, 8(5), 349–361.

Shahidi, F. (Ed.). (2005). Bailey's Industrial Oil and Fat Products (6th ed.). John Wiley & Sons.

Simopoulos, A. P. (2002). "The importance of the ratio of omega-6/omega-3 essential fatty acids." Biomedicine & Pharmacotherapy, 56(8), 365–379.

Simopoulos, A. P. (2011). "Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: Nutritional implications for chronic diseases." Biomedicine & Pharmacotherapy, 65(7), 502–509.

Skoog, D. A., Holler, F. J., & Crouch, S. R. (2017). Principles of Instrumental Analysis (7th ed.). Cengage Learning.

Smit, N., Vicanova, J., & Pavel, S. (2009). "The hunt for natural skin whitening agents." International Journal of Molecular Sciences, 10(12), 5326–5349.

Solano, F. (2014). "Melanins: Skin pigments and much more-types, structural models, biological functions, and formation routes." New Journal of Science, 2014, 1–28.

Solano, F., Briganti, S., Picardo, M., & Ghanem, G. (2006). "Hypopigmenting agents: An updated review on biological, chemical and clinical aspects." Pigment Cell Research, 19(6), 550–571.

Stauffer, C.E. (1996) In Fats and Oils. American Association of Cereal Chemists Inc, Eagan Press, St Paul MN, USA. https://doi.org/10.1094/9780913250907

Swadesh, J. K. (2000). HPLC: Practical and Industrial Applications (2nd ed.). CRC Press.

Thurman, E. M., & Mills, M. S. (1998). Solid-Phase Extraction: Principles and Practice. John Wiley & Sons.

Uthicke, S. (1999). Sediment bioturbation and impact of feeding activity of Holothuria (Halodeima) atra and Stichopus chloronotus, two sediment-feeding holothurians, at Lizard Island, Great Barrier Reef. Bulletin of Marine Science, 64(1), 129-141.

Uthicke, S. (2001). Nutrient regeneration by abundant coral reef holothurians. Journal of Experimental Marine Biology and Ecology, 265(2), 153-170.

Watson, J. T., & Sparkman, O. D. (2007). Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation (4th ed.). Wiley.

Wijesekara, I., Pangestuti, R., & Kim, S. K. (2011). "Biological activities and potential health benefits of sulfated polysaccharides derived from marine algae." Carbohydrate Polymers, 84(1), 14–21.

Wijesinghe, W. A. J. P., & Jeon, Y. J. (2012). "Exploiting biological activities of brown seaweed Ecklonia cava for potential industrial applications: A review." International Journal of Food Sciences and Nutrition, 63(3), 225–235.

Wu, G. (2013). "Functional amino acids in nutrition and health." Amino Acids, 45(3), 407–411.

Yang, H., Hamel, J. F., & Mercier, A. (2015). The sea cucumber Stichopus japonicus: History, biology, and aquaculture. Academic Press.

Yang, H., Yuan, X., Zhou, Y., Mao, Y., Zhang, T., & Liu, Y. (2005). Effects of Temperature on Growth and Energy Budget of the Sea Cucumber, Stichopus japonicus Selenka. Aquaculture Research, 46(2), 296–303.

Zasloff, M. (2002). "Antimicrobial peptides of multicellular organisms." Nature, 415(6870), 389–395.

Zhong, Y., Khan, M. A., & Shahidi, F. (2007). Compositional characteristics and antioxidant properties of fresh and processed sea cucumber (Stichopus japonicus). Journal of Agricultural and Food Chemistry, 55(4), 1188-1192.

Zohdi, R. M., Zakaria, Z. A., & Yusof, N. (2011). Sea Cucumbers (Holothuria atra): Antifungal Properties and Potential Uses. Biomedical Research International, 2011, 1-6.

Zohdi, R. M., Zakaria, Z. A., Yusof, N., & Mustapha, N. M. (2011). "Sea cucumber (Stichopus hermanni) based hydrogel to treat burn wounds in rats." Journal of Biomedical Science, 18(1), 1–7.

Zolghadri, S., Bahrami, A., Hassan Khan, M. T., Munoz-Munoz, J., Garcia-Molina, F., Garcia-Canovas, F., & Saboury, A. A. (2019). "A comprehensive review on tyrosinase inhibitors." Journal of Enzyme Inhibition and Medicinal Chemistry, 34(1), 279–309.

Hsu, C. K., Chang, C. T., Lu, H. Y., & Chung, Y. C. (2007). Inhibitory effects of the water extracts of Lavendula sp. on mushroom tyrosinase activity. Food Chemistry, 105(3), 1099–1105.

Husni, A. A., Shin, I. S., You, S. G., & Chung, D. (2009). Antioxidant properties of water and aqueous ethanol extracts and their crude saponin fractions from a Far-Eastern Sea cucumber, Stichopus japonicus. Food Science and Biotechnology, 18(2), 419–424.

Husni, A., Shin, I. S., & Chung, D. (2014). Effect of extraction methods on antifungal activity of sea cucumber (Stichopus japonicus). Agritech, 34(1).

Husni, A., Jeon, J. S., Um, B. H., Han, N. S., & Chung, D. (2011). Tyrosinase inhibition by water and ethanol extracts of a Far Eastern Sea cucumber, Stichopus japonicus. Journal of the Science of Food and Agriculture, 91(9), 1541–1547.

Chang, T.-S. (2009). An updated review of tyrosinase inhibitors. International Journal of Molecular Sciences, 10(6), 2440–2475. https://doi.org/10.3390/ijms10062440

Min, K., Park, G. W., Yoo, Y. J., & Lee, J.-S. (2019). A perspective on the biotechnological applications of the versatile tyrosinase. Bioresource Technology, 289, 121730. https://doi.org/10.1016/j.biortech.2019.121730

Diterbitkan

2025-04-29

Cara Mengutip

POTENSI TERIPANG Stichopus japonicus SEBAGAI ANTIJAMUR, ANTIOKSIDAN, DAN PENGHAMBATAN TIROSINASE. (2025). Penerbit Kamiya Jaya Aquatic. https://kjaquatic.com/index.php/penerbitkamiyajayaaquatic/article/view/24