harnessing ecofriendly antifouling of agelasine alkaloids

Description

harnessing ecofriendly antifouling of agelasine alkaloids

Penulis

Walter Balansa, P.hD
Frets J. Rieuwpassa, M.Si
Dr.rer.nat. Riyanti, ST, M. Biotech
Novriyandi Hanif, DSc

Sinopsis

Biofouling, the accumulation of organisms on submerged surfaces, imposes significant economic, operational, and environmental burdens on the maritime and aquaculture industries. Traditional antifouling methods rely on toxic chemicals that damage ecosystems. The monograph “Harnessing Ecofriendly Antifouling of Agelasine Alkaloids” explores the potential of agelasine alkaloids derived from the marine sponge Agelas nakamurai as a sustainable solution.

This research reveals the unique mechanism of agelasine targeting acetylcholinesterase, preventing the attachment of biofouling organisms. Using a multidisciplinary approach, it incorporates fieldwork, molecular docking, and toxicity testing, demonstrating that agelasines outperforms commercial agents like Irgarol_1501, Seanin_211, Diruon and Selektope. Compound modification through glucuronidation and sulfation enhances bioactivity while reducing toxicity.

This monograph provides an in-depth insight into the methodology, results, and implications of adopting agelasine derivatives as an eco-friendly antifouling agents. It offers an innovative solution for the maritime and aquaculture industries while safeguarding marine ecosystems sustainably.

Referensi:

Balansa, W., Rieuwpassa, F. J., Riyanti, & Hanif, N. (2024). harnessing ecofriendly antifouling of agelasine alkaloids. Ternate PT. Kamiya Jaya Aquatic. https://kjaquatic.com/product/harnessing-ecofriendly-antifouling-of-agelasine-alkaloids/